Warning Signals
Diseases & Conditions Linked with Loss of Smell Include:
Traumatic Brain Injury (TBI):
Severe head trauma can serve as an early warning sign, triggering loss or altered sense of smell as a prodromal symptom.
Cardiovascular Disease (CVD):
Early stages of CVD can exhibit olfactory dysfunction, including the loss of smell, offering a potential prodromal indicator of underlying vascular damage.
Infectious Diseases:
Various infectious diseases, including respiratory viruses like coronaviruses, can cause acute loss of smell, while those with Long COVID may experience loss or distorted (parosmia) smell.
Alzheimer’s Disease:
Olfactory dysfunction, such as loss of smell, often presents as an early prodromal symptom in individuals at risk of developing Alzheimer’s disease.
Parkinson’s Disease:
Diminished sense of smell acts as an early warning sign, preceding motor symptoms, and serving as a prodromal indication of Parkinson’s disease.
Chronic Rhinosinusitis:
Long-lasting inflammation in the nasal passages and sinuses can manifest as an early warning sign, foretelling a potential decline in the sense of smell.
Note that this list is not comprehensive, and there are other conditions or factors that can also impact the sense of smell, including aging. As smell loss can be due to multiple factors it should not be used alone to diagnose a specific disease or condition. Further, the absence of an abnormal test result does not rule out diseases or other conditions. A person with olfactory dysfunction should consult with a healthcare professional.
